About NanGenex Inc.

NanGenex is a Proprietary NanoSolution Technology Platform Company. We provide breakthrough solutions to develop new generations of NanoActive products with significant performance benefits over conventional approaches.

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NanoActive™ Technology

The proprietary NanoActive™ technology gets over the failures and shortcomings of the commercially available top-down milling and high pressure homogenization based technologies. It is a bottom-up continuous flow nano precipitation method for the synthesis of nanoparticles . The properties of the produced nanoparticles can be modified during the process by the precise control and optimization of various reaction parameters (e.g. pressure, temperature, flow rate, pH and concentration).

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Advantage of the NanoActives™

  • Enhanced bioavailability
  • Increased performance of poorly or non-soluble compounds (increased solubility and dissolution rate)
  • Reduced side effect
  • Reduced food-effect
  • New formulation of existing APIs or NCEs
  • Reduced dosage/variability

 

 NanoActive™ Drug wetability test

 

NanoActive™ Drug redispersibility test

 

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Benefits of NanoActive™ Technology

Increased solubility and enhanced bioavailability

Poorly soluble drugs generally have low solubility as well as low dissolution velocity and exhibit a small concentration gradient across the intestinal mucosa, which can result in low, variable absorption and a poor therapeutic response. Based on the understanding that not only the solubility but also the rate of drug dissolution are primary driving forces behind improved pharmacokinetic properties, the reduction in particle size below 200 nm and unique nanostructured particle formation can lead to 100s fold higher solubility and 103-4 fold increased drug concentration in a stable colloid solution by instantaneous redispersibility of the nanostructured drugs.

 

Increased solubility of NanoActive™

 

 

Enhanced bioavailability of NanoActive™

 

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Company News & Events

Latest Press Release

Budapest, Hungary, 31 August 2010

NanGenex to introduce the new GMP compliant industrial scale NanoPilot instrument

Nangenex Inc., the Proprietary NanoSolution Technology Platform Company presents its latest GMP compliant benchtop and pilot pant reactor for the industrial scale production of NanoActive™ nanoparticles.

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Upcoming events

 

November 15-17, 2010 Munich, Germany
BIO - Europe 2010